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Heat Shock 70kDa Protein 8 (HSPA8) (N-Term) Peptide

HSPA8 Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN978309
  • Target See all Hsc70 (HSPA8) products
    Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 8
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-HSPA8 antibody (Catalog #: ARP48445_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))
    Background
    HSPA8 belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA8 is a heat-shock cognate protein. The protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date.The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date.

    Alias Symbols: HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP1, MGC131511, MGC29929, NIP71

    Protein Interaction Partner: DNAJB1,STUB1,ABI1,ALDOB,APOB,BAG1,BAG2,BAG3,BAT3,C4orf14,CCT3,CD40,CITED1,CLTA,COL7A1,CXCR4,CYCS,DNAJA1,DNAJA3,DPP3,DYNLL1,ERH,FBP1,GAK,GCH1,GOT2,HDAC3,HSF1,HSP90AA1,HSPA1A,HSPA8,HSPBP1,HSPH1,JAK2,MAPT,PHC1,PPID,RAF1,RB1,REL,RGS2,SP1,STMN1,STUB1,SUMO4,TADA3,TCERG1,TM4SF1,TSSK6,UBB,UCHL1,YWHAG,YWHAQ,BAG1,BAG2,BAG3,BAG4,BRCA1,C4orf14,CDC5L,CFTR,CITED1,CYCS,DNAJA1,DNAJA3,DNAJB1,DNAJC2,DNAJC3,ERH,FANCC,FBP1,GOT2,GPN1,GPR37,HCFC1,HDAC3,HGS,HNRNPD,HSF1,HSP90AA1,HSPBP1,JAK2,MAPT,P2rx7,PACSIN1,PACSIN2,PACSIN3,PARK2,POLR3D,PPID,PPP1CA,PPP1R12B,PPP1R15A,RBX1,RGS2,RPAP1,RUVBL1,STMN1,STUB1,TADA3,TCERG1,TCP1,TM4SF1,TNFRSF1A,TP53,TP53,TP53,UBC

    Protein Size: 646
    Molecular Weight
    71 kDa
    Gene ID
    3312
    NCBI Accession
    NM_006597, NP_006588
    UniProt
    P11142
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