Heat Shock 70kDa Protein 8 (HSPA8) (N-Term) Peptide
HSPA8
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN978309
Quick Overview for Heat Shock 70kDa Protein 8 (HSPA8) (N-Term) Peptide (ABIN978309)
Target
Hsc70 (HSPA8)
(Heat Shock 70kDa Protein 8 (HSPA8))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HSPA8 antibody (Catalog #: ARP48445_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))
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Background
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HSPA8 belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA8 is a heat-shock cognate protein. The protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date.The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date.
Alias Symbols: HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP1, MGC131511, MGC29929, NIP71
Protein Interaction Partner: DNAJB1,STUB1,ABI1,ALDOB,APOB,BAG1,BAG2,BAG3,BAT3,C4orf14,CCT3,CD40,CITED1,CLTA,COL7A1,CXCR4,CYCS,DNAJA1,DNAJA3,DPP3,DYNLL1,ERH,FBP1,GAK,GCH1,GOT2,HDAC3,HSF1,HSP90AA1,HSPA1A,HSPA8,HSPBP1,HSPH1,JAK2,MAPT,PHC1,PPID,RAF1,RB1,REL,RGS2,SP1,STMN1,STUB1,SUMO4,TADA3,TCERG1,TM4SF1,TSSK6,UBB,UCHL1,YWHAG,YWHAQ,BAG1,BAG2,BAG3,BAG4,BRCA1,C4orf14,CDC5L,CFTR,CITED1,CYCS,DNAJA1,DNAJA3,DNAJB1,DNAJC2,DNAJC3,ERH,FANCC,FBP1,GOT2,GPN1,GPR37,HCFC1,HDAC3,HGS,HNRNPD,HSF1,HSP90AA1,HSPBP1,JAK2,MAPT,P2rx7,PACSIN1,PACSIN2,PACSIN3,PARK2,POLR3D,PPID,PPP1CA,PPP1R12B,PPP1R15A,RBX1,RGS2,RPAP1,RUVBL1,STMN1,STUB1,TADA3,TCERG1,TCP1,TM4SF1,TNFRSF1A,TP53,TP53,TP53,UBC
Protein Size: 646 -
Molecular Weight
- 71 kDa
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Gene ID
- 3312
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NCBI Accession
- NM_006597, NP_006588
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UniProt
- P11142
Target
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