HtrA Serine Peptidase 4 (HTRA4) (Middle Region) Peptide
Quick Overview for HtrA Serine Peptidase 4 (HTRA4) (Middle Region) Peptide (ABIN978360)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HTRA4 antibody (Catalog #: ARP55603_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HTRA4 (HtrA Serine Peptidase 4 (HTRA4))
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Background
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HTRA4 is a member of the HtrA family of proteases. The protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.
Alias Symbols: FLJ90724
Protein Size: 476 -
Molecular Weight
- 51 kDa
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Gene ID
- 203100
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NCBI Accession
- NM_153692, NP_710159
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UniProt
- P83105
Target
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