Islet Amyloid Polypeptide (IAPP) (N-Term) Peptide
Quick Overview for Islet Amyloid Polypeptide (IAPP) (N-Term) Peptide (ABIN978369)
Target
Origin
Source
Application
-
-
Protein Region
- N-Term
-
Sequence
- MGILKLQVFL IVLSVALNHL KATPIESHQV EKRKCNTATC ATQRLANFLV
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-IAPP Antibody(ARP41728_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
Islet Amyloid Polypeptide (IAPP) peptide (BSA)
IAPP Reactivity: Rat Host: Synthetic WB, Imm, SDS
Islet Amyloid Polypeptide (IAPP) peptide (BSA)IAPP Reactivity: Mouse Host: Synthetic WB, Imm, SDS
Islet Amyloid Polypeptide (IAPP) peptide (BSA)IAPP Reactivity: Human Host: Synthetic WB, Imm, SDS
Islet Amyloid Polypeptide (IAPP) peptide (Ovalbumin)IAPP Reactivity: Rat Host: Synthetic WB, Imm, SDS
Islet Amyloid Polypeptide (IAPP) peptide (Ovalbumin)IAPP Reactivity: Mouse Host: Synthetic WB, Imm, SDS
Islet Amyloid Polypeptide (IAPP) peptide (Ovalbumin)IAPP Reactivity: Human Host: Synthetic WB, Imm, SDS
Islet Amyloid Polypeptide (IAPP) peptide (Ovalbumin)IAPP Reactivity: Human Host: Synthetic WB, Imm, SDS
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))
-
Background
-
Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
Alias Symbols: AMYLIN, DAP, IAP
Protein Interaction Partner: COL25A1,PCSK1,PCSK2,PDX1,RAMP1,RAMP2
Protein Size: 89 -
Molecular Weight
- 4 kDa
-
Gene ID
- 3375
-
NCBI Accession
- NM_000415, NP_000406
-
UniProt
- P10997
Target
-
