Integrin-Binding Sialoprotein (IBSP) Peptide
IBSP
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978373
$160.46
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100 μg
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United States
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Quick Overview for Integrin-Binding Sialoprotein (IBSP) Peptide (ABIN978373)
Target
IBSP
(Integrin-Binding Sialoprotein (IBSP))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-IBSP antibody (Catalog #: ARP36681_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IBSP (Integrin-Binding Sialoprotein (IBSP))
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Background
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The protein encoded by the IBSP gene is a major structural protein of the bone matrix. It constitutes approximately 12 % of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
Alias Symbols: BSP, BNSP, SP-II, BSP-II
Protein Size: 317 -
Molecular Weight
- 35 kDa
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Gene ID
- 3381
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NCBI Accession
- NM_004967, NP_004958
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UniProt
- P21815
Target
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