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Intercellular Adhesion Molecule 5 (ICAM5) (N-Term) Peptide

ICAM5 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN978378
  • Target See all ICAM5 products
    ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ICAM5 antibody (Catalog #: ARP45452_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))
    Background
    ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: TLCN, TLN

    Protein Interaction Partner: ITGAL,ITGB2,PSEN1,PSEN2,PSEN1,PSEN2

    Protein Size: 924
    Molecular Weight
    95 kDa
    Gene ID
    7087
    NCBI Accession
    NM_003259, NP_003250
    UniProt
    Q9UMF0
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