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Isoprenylcysteine Carboxyl Methyltransferase (ICMT) Peptide

ICMT Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN978380
  • Target See all ICMT products
    ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ICMT antibody (Catalog #: ARP46894_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))
    Synonyms
    HSTE14 Peptide, MST098 Peptide, MSTP098 Peptide, PCCMT Peptide, PCMT Peptide, PPMT Peptide, 1700008E11Rik Peptide, C80758 Peptide, Gm13095 Peptide, OTTMUSG00000010406 Peptide, STE14 Peptide, pcCMT Peptide, fcmt Peptide, im:6895697 Peptide, zgc:110258 Peptide, isoprenylcysteine carboxyl methyltransferase Peptide, cobalt-zinc-cadmium resistance protein Peptide, Isoprenylcysteine carboxyl methyltransferase Peptide, isoprenylcysteine carboxylmethyltransferase family protein Peptide, isoprenylcysteine carboxyl methyltransferase S homeolog Peptide, ICMT Peptide, Icmt Peptide, icmt Peptide, Bcen_5417 Peptide, Acid_0983 Peptide, Bcenmc03_4825 Peptide, RPIC_RS08670 Peptide, Mesil_1887 Peptide, Slip_1333 Peptide, Deba_2487 Peptide, Bresu_2161 Peptide, MPET_RS04760 Peptide, MPET_RS08305 Peptide, Saut_0066 Peptide, Intca_3523 Peptide, Deima_2891 Peptide, Despr_1203 Peptide, Deipr_0831 Peptide, Theth_0229 Peptide, icmt.S Peptide
    Background
    ICMT is the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.

    Alias Symbols: HSTE14, MGC39955, MST098, MSTP098, PCCMT, PCMT, PPMT

    Protein Interaction Partner: HRAS,RAC1,RAC2,RHOA,RAC2,RHOA

    Protein Size: 284
    Molecular Weight
    32 kDa
    Gene ID
    23463
    NCBI Accession
    NM_012405, NP_036537
    UniProt
    O60725
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