Isoprenylcysteine Carboxyl Methyltransferase (ICMT) Peptide
ICMT
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978380
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Isoprenylcysteine Carboxyl Methyltransferase (ICMT) Peptide (ABIN978380)
Target
ICMT
(Isoprenylcysteine Carboxyl Methyltransferase (ICMT))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ICMT antibody (Catalog #: ARP46894_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))
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Background
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ICMT is the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.
Alias Symbols: HSTE14, MGC39955, MST098, MSTP098, PCCMT, PCMT, PPMT
Protein Interaction Partner: HRAS,RAC1,RAC2,RHOA,RAC2,RHOA
Protein Size: 284 -
Molecular Weight
- 32 kDa
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Gene ID
- 23463
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NCBI Accession
- NM_012405, NP_036537
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UniProt
- O60725
Target
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