Iduronate 2-Sulfatase (IDS) (N-Term) Peptide
IDS
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978399
Quick Overview for Iduronate 2-Sulfatase (IDS) (N-Term) Peptide (ABIN978399)
Target
IDS
(Iduronate 2-Sulfatase (IDS))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Sequence
- SFPPYHPSSE KYENTKTCRG PDGELHANLL CPVDVLDVPE GTLPDKQSTE
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-IDS Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- IDS (Iduronate 2-Sulfatase (IDS))
-
Background
-
Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.
Alias Symbols: MPS2, SIDS
Protein Size: 550 -
Molecular Weight
- 59 kDa
-
Gene ID
- 3423
-
NCBI Accession
- NM_000202, NP_000193
-
UniProt
- P22304
Target
-
You are here:
