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Insulin-Like Growth Factor 2 (IGF2) (C-Term) Peptide

IGF2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN978432

Quick Overview for Insulin-Like Growth Factor 2 (IGF2) (C-Term) Peptide (ABIN978432)

Target

IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Origin

Human

Source

  • 2
  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    YDTWKQSTQR LRRGLPALLR ARRGHVLAKE LEAFREAKRH RPLIALPTQD

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-IGF2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    IGF2 (Insulin-Like Growth Factor 2 (IGF2))

    Background

    This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: C11orf43, FLJ22066, FLJ44734, INSIGF, pp9974, IGF-II, PP9974

    Protein Size: 236

    Molecular Weight

    25 kDa

    Gene ID

    3481

    NCBI Accession

    NM_001127598, NP_001121070

    UniProt

    C9JAF2
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