Immunoglobulin Superfamily, Member 8 (IGSF8) (Middle Region) Peptide
IGSF8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all IGSF8 products
- IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LAVEAGAPYA ERLAAGELRL GKEGTDRYRM VVGGAQAGDA GTYHCTAAEW
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IGSF8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))
- Background
-
IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. IGSF8 may also play a role on integrin-dependent morphology and motility functions. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
Alias Symbols: CD316, CD81P3, EWI2, PGRL, EWI-2, KCT-4, LIR-D1
Protein Size: 613 - Molecular Weight
- 65 kDa
- Gene ID
- 93185
- NCBI Accession
- NM_052868, NP_443100
- UniProt
- Q969P0
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