IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (Middle Region) Peptide
-
- Target See all IKZF1 products
- IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))
- Protein Region
- Middle Region
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IKZF1 antibody (Catalog #: ARP31470_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))
- Background
-
IKZF1 binds and activates the enhancer (delta-A element) of the CD3-delta gene. It functions in the specification and the maturation of the T-lymphocyte. It also interacts with a critical control element in the TDT (terminal deoxynucleotidyltransferase) promoter as well as with the promoters for other genes expressed during early stages of B- and T-cell development.
Alias Symbols: Hs.54452, IK1, IKAROS, LYF1, PRO0758, ZNFN1A1, hIk-1
Protein Interaction Partner: AP2M1,CHD3,CTBP1,GTF2B,HDAC1,HDAC2,IKZF2,IKZF3,IKZF4,RBBP8,SAP18,SIN3A,SIN3B,SMARCA4,TBP,UBE2I,AP2M1,CHD4,CTBP1,GTF2B,HDAC1,HDAC2,HDAC3,HDAC4,HDAC5,HDAC7,Hdac1,IKZF2,IKZF4,IKZF5,Ikzf3,NCOR2,RBBP8,SIN3A,SIN3B,Sin3a,Sin3b,TBP,UBE2I
Protein Size: 519 - Molecular Weight
- 57 kDa
- Gene ID
- 10320
- NCBI Accession
- NM_006060, NP_006051
- UniProt
- Q13422
-