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Interleukin 11 Receptor, alpha (IL11RA) (Middle Region) Peptide

IL11RA Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN978470
$160.46
Plus shipping costs $50.00
100 μg
Shipping to: United States
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Quick Overview for Interleukin 11 Receptor, alpha (IL11RA) (Middle Region) Peptide (ABIN978470)

Target

IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Origin

Human

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-IL11RA antibody (Catalog #: ARP46465_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

    Background

    Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. IL11RA is the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain.Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.

    Alias Symbols: MGC2146, CRSDA

    Protein Interaction Partner: IL11

    Protein Size: 422

    Molecular Weight

    43 kDa

    Gene ID

    3590

    NCBI Accession

    NM_004512, NP_004503

    UniProt

    Q14626
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