Interleukin 27 (IL27) (C-Term) Peptide
IL27
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all IL-27 (IL27) products
- IL-27 (IL27) (Interleukin 27 (IL27))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AQVSWPQLLS TYRLLHSLEL VLSRAVRELL LLSKAGHSVW PLGFPTLSPQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IL27 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IL-27 (IL27) (Interleukin 27 (IL27))
- Synonyms
- IL-27 Peptide, IL-27A Peptide, IL27A Peptide, IL27p28 Peptide, IL30 Peptide, p28 Peptide, RGD1561420 Peptide, IL27 Peptide, IL-27p28 Peptide, Il30 Peptide, interleukin 27 Peptide, IL27 Peptide, Il27 Peptide
- Background
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The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
Alias Symbols: IL-27, IL-27A, IL27p28, IL30, MGC71873, p28, IL27A
Protein Interaction Partner: IL27RA
Protein Size: 243 - Molecular Weight
- 27 kDa
- Gene ID
- 246778
- NCBI Accession
- NM_145659, NP_663634
- UniProt
- Q8NEV9
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