Interleukin 3 Receptor, alpha (IL3RA) (C-Term) Peptide
IL3RA
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978509
Quick Overview for Interleukin 3 Receptor, alpha (IL3RA) (C-Term) Peptide (ABIN978509)
Target
IL3RA
(Interleukin 3 Receptor, alpha (IL3RA))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- IQKRMQPVIT EQVRDRTSFQ LLNPGTYTVQ IRARERVYEF LSAWSTPQRF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-IL3RA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
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Background
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The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y.
Alias Symbols: CD123, IL3R, IL3RAY, IL3RX, IL3RY, MGC34174, hIL-3Ra
Protein Interaction Partner: CISH,CSF2,CSF2RB,IL3,JAK1,JAK2,CISH,IL3
Protein Size: 378 -
Molecular Weight
- 41 kDa
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Gene ID
- 3563
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NCBI Accession
- NM_002183, NP_002174
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UniProt
- P26951
Target
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