Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1) Peptide
IMPDH1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN978539
Quick Overview for Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1) Peptide (ABIN978539)
Target
IMPDH1
(Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-IMPDH1 antibody (Catalog #: ARP54363_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))
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Background
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IMPDH1 acts as a homotetramer to regulate cell growth. It is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10).
Alias Symbols: DKFZp781N0678, IMPD, IMPD1, LCA11, RP10, sWSS2608
Protein Size: 563 -
Molecular Weight
- 62 kDa
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Gene ID
- 3614
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NCBI Accession
- NM_183243, NP_899066
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UniProt
- P20839
Target
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