Inhibitor of Growth Family, Member 1 (ING1) (N-Term) Peptide
ING1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ING1 products
- ING1 (Inhibitor of Growth Family, Member 1 (ING1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SPAERLVAEA DEGGPSAITG MGLCFRCLLF SFSGRSGVEG GRVDLNVFGS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ING1 Antibody(ARP50511_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ING1 (Inhibitor of Growth Family, Member 1 (ING1))
- Background
-
ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.
Alias Symbols: p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a
Protein Interaction Partner: TP53,BRMS1,BRMS1L,C20orf20,DMAP1,EP300,HDAC1,HDAC2,KAT2B,PCNA,RBBP4,RBBP7,RBP1,SAP30,SFN,SIN3A,TP53,YWHAB,YWHAE,YWHAG,YWHAH,YWHAQ,YWHAZ,ACTL6A,ARID1A,C20orf20,CDKN2A,CREBBP,DMAP1,EP300,ESR1,HDAC1,HDAC2,HHT1,HHT2,HIST2H3A,HIST2H3C,HIST4H4,KAT2B,KPNA2,KPNB1
Protein Size: 422 - Molecular Weight
- 47 kDa
- Gene ID
- 3621
- NCBI Accession
- NM_005537, NP_005528
- UniProt
- Q9UK53
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