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Inhibitor of Growth Family, Member 1 (ING1) (N-Term) Peptide

ING1 Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN978546

Quick Overview for Inhibitor of Growth Family, Member 1 (ING1) (N-Term) Peptide (ABIN978546)

Target

ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

N-Term

Sequence

SPAERLVAEA DEGGPSAITG MGLCFRCLLF SFSGRSGVEG GRVDLNVFGS

Characteristics

This is a synthetic peptide designed for use in combination with anti-ING1 Antibody(ARP50511_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
Inhibitor of Growth Family, Member 1 (ING1) peptide
ING1 Host: Synthetic Sodium azide

Inhibitor of Growth Family, Member 1 (ING1) peptide
ING1 Reactivity: Human Host: Synthetic BP, WB

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Background

ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.

Alias Symbols: p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a

Protein Interaction Partner: TP53,BRMS1,BRMS1L,C20orf20,DMAP1,EP300,HDAC1,HDAC2,KAT2B,PCNA,RBBP4,RBBP7,RBP1,SAP30,SFN,SIN3A,TP53,YWHAB,YWHAE,YWHAG,YWHAH,YWHAQ,YWHAZ,ACTL6A,ARID1A,C20orf20,CDKN2A,CREBBP,DMAP1,EP300,ESR1,HDAC1,HDAC2,HHT1,HHT2,HIST2H3A,HIST2H3C,HIST4H4,KAT2B,KPNA2,KPNB1

Protein Size: 422

Molecular Weight

47 kDa

Gene ID

3621

NCBI Accession

NM_005537, NP_005528

UniProt

Q9UK53

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