Inhibitor of Growth Family, Member 4 (ING4) Peptide
Quick Overview for Inhibitor of Growth Family, Member 4 (ING4) Peptide (ABIN978551)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ING4 antibody (Catalog #: ARP50608_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ING4 (Inhibitor of Growth Family, Member 4 (ING4))
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Background
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ING4 is a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway.This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins.
Alias Symbols: MGC12557, my036, p29ING4
Protein Interaction Partner: EP300,RELA,TP53,EGLN1,EP300,MYST2,RELA,TP53,CDKN2A,EGLN1,EP300,G3BP2,HHT1,HHT2,HIST2H3C,HIST3H3,MEAF6,MYST2,PHF15,PHF16,PHF17,PPFIA1,RELA,TP53,Trp53,UBE2D2
Protein Size: 248 -
Molecular Weight
- 28 kDa
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Gene ID
- 51147
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NCBI Accession
- NM_016162, NP_057246
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UniProt
- Q9UNL4
Target
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