Insulin Receptor (INSR) (Middle Region) Peptide
INSR
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978574
Quick Overview for Insulin Receptor (INSR) (Middle Region) Peptide (ABIN978574)
Target
Insulin Receptor (INSR)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-INSR antibody (Catalog #: ARP41374_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Insulin Receptor (INSR)
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Background
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This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. INSR mediates the metabolic functions of insulin. INSR binding to insulin stimulates association of the receptor with downstream media
Alias Symbols: CD220, HHF5
Protein Interaction Partner: HMGA1,CSK,GRB10,IRS1,IRS1,IRS2,JAK1,PIK3R1,PIK3R1,SHC1,SOCS1,SOCS6,ACP1,ADRB2,AHSG,ARF1,ARHGAP26,CALM1,CALM3,CALM3,CAV1,CAV3,CBL,CEACAM1,CRK,CRKL,CSK,DOK1,DOK4,DOK5,ENPP1,FABP4,FRS2,GAB1,GNB2L1,GRB10,GRB14,GRB7,HRAS,IGF1R,IGF2,INS,INSR,INSRR,IRS1,IRS2,JAK1,JAK2,KHDRBS1,KRT27,MAD2L1,MAPK3,PIK3R1,PIK3R3,PLCG1,PRKCA,PRKCD,PTK2,PTPN1,PTPN11,PTPN12,PTPN2,PTPN6,PTPRC,PTPRF,RAF1,RASA1,SH2B1,SH2B2,SHC1,SMAD2,SNX1,SNX2,SNX4,SNX6,SOCS1,SOCS2,SOCS3,SOCS6,SORBS1,SRC,STAT5A,STAT5B,SYNCRIP,VAV1,VAV3,YWHAB,AHSG,CAV1,CSK,ENPP1,FRS2,GRB10,GRB14,GRB2,GRB7,Grb14,HRAS,INPPL1,INSRR,IRS1,IRS2,JAK2,KHDRBS1,MAPK1,MAPK3,PRKCD,PTPN1,PTPN11,PTPN6,RASA1,SH2B1,SHC1,SMAD2,SNX1,SNX2,SNX4,SNX6,SOCS3,SORBS1,SYNCRIP,VAV1,VAV3
Protein Size: 1382 -
Molecular Weight
- 154 kDa
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Gene ID
- 3643
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NCBI Accession
- NM_000208, NP_000199
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UniProt
- P06213
Target
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