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Integrator Complex Subunit 12 (INTS12) (N-Term) Peptide

INTS12 Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN978575

Quick Overview for Integrator Complex Subunit 12 (INTS12) (N-Term) Peptide (ABIN978575)

Target

INTS12 (Integrator Complex Subunit 12 (INTS12))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

N-Term

Characteristics

This is a synthetic peptide designed for use in combination with anti-INTS12 antibody (Catalog #: ARP51223_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
Integrator Complex Subunit 12 (INTS12) peptide
INTS12 Reactivity: Mammalian Host: Synthetic BP, WB, IHC

Integrator Complex Subunit 12 (INTS12) (C-Term) peptide
INTS12 Reactivity: Human, Rat Host: Synthetic BP, WB

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

INTS12 (Integrator Complex Subunit 12 (INTS12))

Background

INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and U2 (RNU2).INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM].

Alias Symbols: INT12, PHF22, SBBI22

Protein Size: 462

Molecular Weight

49 kDa

Gene ID

57117

NCBI Accession

NM_020395, NP_065128

UniProt

Q96CB8

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