Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (C-Term) Peptide
IRAK4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978590
Quick Overview for Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (C-Term) Peptide (ABIN978590)
Target
IRAK4
(Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- TGLPAVDEHR EPQLLLDIKE EIEDEEKTIE DYIDKKMNDA DSTSVEAMYS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-IRAK4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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Background
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This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: IPD1, NY-REN-64, REN64, IRAK-4
Protein Interaction Partner: PELI2,IRAK1,MYD88,PELI1,PELI2,TBPL1,TICAM2,TRAF6,IRAK1,MYD88,PELI1,PELI2,PELI3,TIRAP,TRAF6,UBC
Protein Size: 336 -
Molecular Weight
- 36 kDa
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Gene ID
- 51135
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NCBI Accession
- NM_001145256, NP_001138728
Target
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