Interferon Regulatory Factor 8 (IRF8) Peptide
IRF8
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN978615
Quick Overview for Interferon Regulatory Factor 8 (IRF8) Peptide (ABIN978615)
Target
IRF8
(Interferon Regulatory Factor 8 (IRF8))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-IRF8 antibody (Catalog #: P100841_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IRF8 (Interferon Regulatory Factor 8 (IRF8))
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Background
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Interferon consensus sequence-binding protein (Ion ChannelSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
Alias Symbols: ICSBP, IRF-8, ICSBP1, H-ICSBP
Protein Interaction Partner: COPS2,IRF1,IRF2,SMURF2,SPI1,TRAF6,ZBTB17,COPS2,ETV6,IRF1,IRF2,IRF8,NFKB1,RELA,TRIM21,UBC
Protein Size: 426 -
Molecular Weight
- 48 kDa
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Gene ID
- 3394
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NCBI Accession
- NM_002163, NP_002154
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UniProt
- Q02556
Target
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