Interferon Regulatory Factor 8 (IRF8) (Middle Region) Peptide
IRF8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all IRF8 products
- IRF8 (Interferon Regulatory Factor 8 (IRF8))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IRF8 antibody (Catalog #: P100842_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IRF8 (Interferon Regulatory Factor 8 (IRF8))
- Synonyms
- zgc:92252 Peptide, IRF8 Peptide, MGC140338 Peptide, DKFZp469B0320 Peptide, H-ICSBP Peptide, ICSBP Peptide, ICSBP1 Peptide, IRF-8 Peptide, icsbp1 Peptide, AI893568 Peptide, Icsbp1 Peptide, Myls Peptide, interferon regulatory factor 8 Peptide, interferon regulatory factor 8 L homeolog Peptide, irf8 Peptide, IRF8 Peptide, irf8.L Peptide, Irf8 Peptide
- Background
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Interferon regulatory factor 8 (IRF8, interferon consensus sequence-binding protein, ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-. and IFN-.. IRF family proteins also control expression of IFN-. and IFN-.-regulated genes that are induced by viral infection.
Alias Symbols: H-ICSBP, ICSBP, ICSBP1, IRF-8
Protein Interaction Partner: COPS2,IRF1,IRF2,SMURF2,SPI1,TRAF6,ZBTB17,COPS2,ETV6,IRF1,IRF2,IRF8,NFKB1,RELA,TRIM21,UBC
Protein Size: 426 - Molecular Weight
- 48 kDa
- Gene ID
- 3394
- NCBI Accession
- NM_002163, NP_002154
- UniProt
- Q02556
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