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Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (N-Term) Peptide

ITCH Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN978648
  • Target See all ITCH products
    ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ITCH antibody (Catalog #: ARP43347_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
    Background
    Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like prot

    Alias Symbols: AIF4, AIP4, NAPP1, dJ468O1.1

    Protein Interaction Partner: ATN1,HHV4gp002,RNF11,TP73,ATN1,CBL,CBLC,CPSF6,DTX1,ITCH,JUN,NDFIP2,NEDD9,NOTCH1,NUMB,OCLN,POLR2A,RNF11,SGK3,SH3GL2,TP73,TRPC4,TRPV1,TRPV4,ARR3,ARRB1,ARRB2,ATN1,CFLAR,CXCR4,DTX1,ERBB4,ITCH,JUN,N4BP1,NEDD9,NFE2,NUMB,RIPK1,RNF11,SCNN1A,SCNN1B,SFN,TP53,TP73,UBC,UBE2L3,USP13,USP9X,YAP1

    Protein Size: 862
    Molecular Weight
    99 kDa
    Gene ID
    83737
    NCBI Accession
    NM_031483, NP_113671
    UniProt
    A9Z1X3
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