Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (N-Term) Peptide
ITCH
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978648
Quick Overview for Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (N-Term) Peptide (ABIN978648)
Target
ITCH
(Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ITCH antibody (Catalog #: ARP43347_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
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Background
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Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like prot
Alias Symbols: AIF4, AIP4, NAPP1, dJ468O1.1
Protein Interaction Partner: ATN1,HHV4gp002,RNF11,TP73,ATN1,CBL,CBLC,CPSF6,DTX1,ITCH,JUN,NDFIP2,NEDD9,NOTCH1,NUMB,OCLN,POLR2A,RNF11,SGK3,SH3GL2,TP73,TRPC4,TRPV1,TRPV4,ARR3,ARRB1,ARRB2,ATN1,CFLAR,CXCR4,DTX1,ERBB4,ITCH,JUN,N4BP1,NEDD9,NFE2,NUMB,RIPK1,RNF11,SCNN1A,SCNN1B,SFN,TP53,TP73,UBC,UBE2L3,USP13,USP9X,YAP1
Protein Size: 862 -
Molecular Weight
- 99 kDa
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Gene ID
- 83737
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NCBI Accession
- NM_031483, NP_113671
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UniProt
- A9Z1X3
Target
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