Lysine (K)-Specific Demethylase 4C (KDM4C) (Middle Region) Peptide
KDM4C
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978700
Quick Overview for Lysine (K)-Specific Demethylase 4C (KDM4C) (Middle Region) Peptide (ABIN978700)
Target
KDM4C
(Lysine (K)-Specific Demethylase 4C (KDM4C))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-JMJD2C antibody (Catalog #: ARP32974_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))
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Background
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JMJD2C is a member of the Jumonji domain 2 (JMJD2) family. It contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.
Alias Symbols: FLJ25949, GASC1, JHDM3C, JMJD2C, KIAA0780, bA146B14.1
Protein Size: 1056 -
Molecular Weight
- 120 kDa
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Gene ID
- 23081
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NCBI Accession
- NM_001146695, NP_001140167
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UniProt
- F5H347
Target
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