Lysine (K)-Specific Demethylase 6B (Kdm6b) (N-Term) Peptide
Kdm6b
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978703
Quick Overview for Lysine (K)-Specific Demethylase 6B (Kdm6b) (N-Term) Peptide (ABIN978703)
Target
Kdm6b
(Lysine (K)-Specific Demethylase 6B (Kdm6b))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-JMJD3 antibody (Catalog #: ARP40101_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
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Background
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JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
Alias Symbols: KIAA0346, JMJD3
Protein Size: 1682 -
Molecular Weight
- 181 kDa
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Gene ID
- 23135
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NCBI Accession
- NM_001080424, NP_001073893
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UniProt
- O15054
Target
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