Lysyl-tRNA Synthetase (KARS) Peptide
KARS
Reactivity: Human
Host: Synthetic
BP, IHC, WB
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- Target See all KARS products
- KARS (Lysyl-tRNA Synthetase (KARS))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KARS antibody (Catalog #: ARP40589_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KARS (Lysyl-tRNA Synthetase (KARS))
- Background
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Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
Alias Symbols: KRS, KARS2, CMTRIB
Protein Interaction Partner: AIMP2,AIMP2,EEF1D,EEF1G,FRS3,GEMIN4,PAFAH1B1,SLC25A6,SOD1,AIMP2,DARS2,EEF1G,MAPK14,PAFAH1B1,SLC25A6
Protein Size: 597 - Molecular Weight
- 66 kDa
- Gene ID
- 3735
- NCBI Accession
- NM_005548, NP_005539
- UniProt
- Q15046
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