Lysyl-tRNA Synthetase (KARS) Peptide
KARS
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN978733
Quick Overview for Lysyl-tRNA Synthetase (KARS) Peptide (ABIN978733)
Target
KARS
(Lysyl-tRNA Synthetase (KARS))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-KARS antibody (Catalog #: ARP40589_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KARS (Lysyl-tRNA Synthetase (KARS))
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Background
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Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
Alias Symbols: KRS, KARS2, CMTRIB
Protein Interaction Partner: AIMP2,AIMP2,EEF1D,EEF1G,FRS3,GEMIN4,PAFAH1B1,SLC25A6,SOD1,AIMP2,DARS2,EEF1G,MAPK14,PAFAH1B1,SLC25A6
Protein Size: 597 -
Molecular Weight
- 66 kDa
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Gene ID
- 3735
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NCBI Accession
- NM_005548, NP_005539
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UniProt
- Q15046
Target
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