Potassium Channel, Subfamily K, Member 10 (KCNK10) (N-Term) Peptide
KCNK10
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978806
Quick Overview for Potassium Channel, Subfamily K, Member 10 (KCNK10) (N-Term) Peptide (ABIN978806)
Target
KCNK10
(Potassium Channel, Subfamily K, Member 10 (KCNK10))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-KCNK10 antibody (Catalog #: ARP35398_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KCNK10 (Potassium Channel, Subfamily K, Member 10 (KCNK10))
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Background
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KCNK10 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is highly expressed in the kidney and pancreas. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. The protein is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Three transcript variants have been identified for this gene. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is highly expressed in the kidney and pancreas. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. The protein is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Three transcript variants have been identified for this gene.
Alias Symbols: K2p10.1, TREK-2, TREK2
Protein Size: 538 -
Molecular Weight
- 60 kDa
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Gene ID
- 54207
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NCBI Accession
- NM_021161, NP_066984
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UniProt
- P57789
Target
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