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Kin of IRRE Like 1 (NEPH1) (Middle Region) Peptide

NEPH1 Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN978984

Quick Overview for Kin of IRRE Like 1 (NEPH1) (Middle Region) Peptide (ABIN978984)

Target

KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

Middle Region

Characteristics

This is a synthetic peptide designed for use in combination with anti-KIRREL antibody (Catalog #: ARP47408_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
Kin of IRRE Like 1 (NEPH1) peptide
NEPH1 Reactivity: Mammalian Host: Synthetic BP, WB, IHC

Kin of IRRE Like 1 (NEPH1) peptide
NEPH1 Host: Synthetic BP, WB, ICo, IDe

Kin of IRRE Like 1 (NEPH1) (C-Term) peptide
NEPH1 Reactivity: Mouse, Rat Host: Synthetic BP, WB, ICo, IDe

Kin of IRRE Like 1 (NEPH1) peptide
NEPH1 Reactivity: Mouse, Rat Host: Synthetic BP, WB, ICo, IDe

Kin of IRRE Like 1 (NEPH1) (phosphorylated) peptide
NEPH1 Reactivity: Mouse, Rat Host: Synthetic BP, WB, ICo, IDe

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))

Background

KIRREL (NEPH1) is a member of the nephrin-like protein family, which includes NEPH2 and NEPH3. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2, MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-337 AY302131.1 1-337 338-3211 BC109193.1 1-2874 3212-3609 AK001707.1 1904-2301 3610-3628 BC082969.1 2273-2291

Alias Symbols: FLJ10845, MGC129542, MGC129543, NEPH1

Protein Interaction Partner: KIRREL,NPHS1,NPHS2,TJP1,KIRREL,NPHS1,TJP1

Protein Size: 593

Molecular Weight

66 kDa

Gene ID

55243

NCBI Accession

NM_018240, NP_060710

UniProt

Q96J84

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