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Klotho (KL) (Middle Region) Peptide

KL Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN978991
  • Target See all Klotho (KL) products
    Klotho (KL)
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 12
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-KL antibody (Catalog #: ARP41554_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Klotho (KL)
    Synonyms
    alpha-kl Peptide, KL Peptide, LOC100223456 Peptide, klotho Peptide, Klotho Peptide, KL Peptide, Kl Peptide, kl Peptide, LOC100533542 Peptide
    Background
    KL is a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: -

    Protein Interaction Partner: IGF1R

    Protein Size: 1012
    Molecular Weight
    116 kDa
    Gene ID
    9365
    NCBI Accession
    NM_004795, NP_004786
    UniProt
    Q9UEF7
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