Prostate Specific Antigen (PSA) (Middle Region) Peptide
PSA
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979078
Quick Overview for Prostate Specific Antigen (PSA) (Middle Region) Peptide (ABIN979078)
Target
Prostate Specific Antigen (PSA)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- LRPGDDSSHD LMLLRLSEPA ELTDAVKVMD LPTQEPALGT TCYASGWGSI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-KLK3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Prostate Specific Antigen (PSA) (AA 235-250) peptide (Ovalbumin)
PSA Reactivity: Human Host: Synthetic WB, Imm, SDS
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Prostate Specific Antigen (PSA)
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Background
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Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
Alias Symbols: APS, KLK2A1, PSA, hK3
Protein Interaction Partner: AR,POLR2A,CTNNB1,KAT5,RUVBL1,A2M,ALB,EPOR,FN1,IGFBP3,PLG,PTHLH,PZP,SEMG1,SEMG2,SERPINA1,SERPINA3,SERPINA5,SLPI,A2M,SERPINA1,SERPINA5
Protein Size: 261 -
Molecular Weight
- 26 kDa
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Gene ID
- 354
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NCBI Accession
- NM_001648, NP_001639
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UniProt
- P07288
Target
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