Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) Peptide
KREMEN1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979110
Quick Overview for Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) Peptide (ABIN979110)
Target
KREMEN1
(Kringle Containing Transmembrane Protein 1 (KREMEN1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-KREMEN1 antibody (Catalog #: ARP44879_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
-
Background
-
KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. It is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Alias Symbols: FLJ31863, KREMEM1, KREMEN, KRM1
Protein Interaction Partner: DKK1
Protein Size: 475 -
Molecular Weight
- 50 kDa
-
Gene ID
- 83999
-
NCBI Accession
- NM_001039570, NP_001034659
-
UniProt
- C1P671
Target
-
You are here:
