Keratin 1 (KRT1) (Middle Region) Peptide
KRT1
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN979113
Quick Overview for Keratin 1 (KRT1) (Middle Region) Peptide (ABIN979113)
Target
Cytokeratin 1 (KRT1)
(Keratin 1 (KRT1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-KRT1 antibody (Catalog #: ARP42278_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
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Background
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KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CK1, EHK1, K1, KRT1A, EHK, EPPK, NEPPK
Protein Interaction Partner: CALB2,DSP,EVPL,F12,KNG1,KRT5,MBL2,PRKCE,YWHAQ,CSTA,DSP,FANCA,FANCC,IVL,KNG1,LOR,MBL2,PI3,PRKCE
Protein Size: 644 -
Molecular Weight
- 66 kDa
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Gene ID
- 3848
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NCBI Accession
- NM_006121, NP_006112
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UniProt
- P04264
Target
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