Keratin 18 (KRT18) Peptide
KRT18
Reactivity: Human, Mouse
Host: Synthetic
BP, IHC, WB
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- Target See all Cytokeratin 18 (KRT18) products
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KRT18 antibody (Catalog #: ARP40205_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
- Background
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KRT18 (Keratin 18) is type I intermediate filament chain. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: K18, CYK18
Protein Interaction Partner: CBL,TRADD,CAMK2A,CASP3,CASP6,CASP7,CASP8,CBL,CCDC85B,CDK1,COL17A1,DEDD,DNAJB6,EGFR,EXOC8,HGS,HSPA1A,HSPA5,KRT15,KRT5,KRT8,LDOC1,MAPK14,NME7,PKD1,PKP2,PNN,PRKCA,PRKCE,RAF1,RHPN2,RPS6KA3,SERPINE1,SHC1,TCHP,TNFRSF1B,TRADD,TUBG1,TUBGCP4,USH2A,YWHAB,YWHAE,YWHAG,YWHAH,YWHAZ,ALK,CBL,CCDC85B,CLEC3B,COL17A1,DEDD,DNAJB6,EXOC8,GRB2,HGS,HSPA4,KRT15,KRT5,KRT72,KRT8,LDOC1,MCC,NME7,PKD1,PKP2,PKP3,PKP3,PNN,PPM1B,PRKCE,TNFRSF1B,TRADD,TUBGCP4,USP32,YWHAQ
Protein Size: 430 - Molecular Weight
- 47 kDa
- Gene ID
- 3875
- NCBI Accession
- NM_000224, NP_000215
- UniProt
- P05783
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