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Keratin 18 (KRT18) Peptide

KRT18 Reactivity: Human, Mouse Host: Synthetic BP, IHC, WB
Catalog No. ABIN979123
  • Target See all Cytokeratin 18 (KRT18) products
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    Origin
    Human, Mouse
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-KRT18 antibody (Catalog #: ARP40206_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    Background
    KRT18 (Keratin 18) is type I intermediate filament chain. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

    Alias Symbols: K18, CYK18

    Protein Interaction Partner: CBL,TRADD,CAMK2A,CASP3,CASP6,CASP7,CASP8,CBL,CCDC85B,CDK1,COL17A1,DEDD,DNAJB6,EGFR,EXOC8,HGS,HSPA1A,HSPA5,KRT15,KRT5,KRT8,LDOC1,MAPK14,NME7,PKD1,PKP2,PNN,PRKCA,PRKCE,RAF1,RHPN2,RPS6KA3,SERPINE1,SHC1,TCHP,TNFRSF1B,TRADD,TUBG1,TUBGCP4,USH2A,YWHAB,YWHAE,YWHAG,YWHAH,YWHAZ,ALK,CBL,CCDC85B,CLEC3B,COL17A1,DEDD,DNAJB6,EXOC8,GRB2,HGS,HSPA4,KRT15,KRT5,KRT72,KRT8,LDOC1,MCC,NME7,PKD1,PKP2,PKP3,PKP3,PNN,PPM1B,PRKCE,TNFRSF1B,TRADD,TUBGCP4,USP32,YWHAQ

    Protein Size: 430
    Molecular Weight
    47 kDa
    Gene ID
    3875
    NCBI Accession
    NM_000224, NP_000215
    UniProt
    P05783
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