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Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (Middle Region) Peptide

LAIR1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN979171

Quick Overview for Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (Middle Region) Peptide (ABIN979171)

Target

LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))

Origin

Human

Source

  • 5
  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequence

    GNAGPYRCIY YKPPKWSEQS DYLELLVKGP TQRPSDNSHN EHAPASQGLK

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-LAIR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))

    Background

    The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.

    Alias Symbols: CD305, LAIR-1

    Protein Size: 270

    Molecular Weight

    30 kDa

    Gene ID

    3903

    NCBI Accession

    NM_021706, NP_068352

    UniProt

    Q6GTX8
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