Lymphocyte Transmembrane Adaptor 1 (LAX1) (Middle Region) Peptide
Quick Overview for Lymphocyte Transmembrane Adaptor 1 (LAX1) (Middle Region) Peptide (ABIN979216)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-LAX1 antibody (Catalog #: ARP47347_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- LAX1 (Lymphocyte Transmembrane Adaptor 1 (LAX1))
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Background
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LAX1 is a single-pass type III membrane protein. It negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
Alias Symbols: FLJ20340, LAX
Protein Interaction Partner: GRAP2,GRB2,LCK,SYK,ZAP70,GRAP2,GRB2
Protein Size: 398 -
Molecular Weight
- 44 kDa
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Gene ID
- 54900
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NCBI Accession
- NM_017773, NP_060243
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UniProt
- Q8IWV1
Target
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