Lamin B Receptor (LBR) (Middle Region) Peptide
LBR
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979221
Quick Overview for Lamin B Receptor (LBR) (Middle Region) Peptide (ABIN979221)
Target
Lamin B Receptor (LBR)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- GANSQKNAFR KNPSDPKLAH LKTIHTSTGK NLLVSGWWGF VRHPNYLGDL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-LBR Antibody(ARP45263_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Lamin B Receptor (LBR)
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Background
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The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Alias Symbols: DHCR14B, LMN2R, MGC9041, PHA
Protein Interaction Partner: AKAP8L,CBX3,CBX5,FNBP4,LBR,LMNB1,PRM1,SRPK1,YWHAG,AKAP8L,CBX3,CBX5,FNBP4,MECP2,YWHAG,tat
Protein Size: 615 -
Molecular Weight
- 71 kDa
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Gene ID
- 3930
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NCBI Accession
- NM_002296, NP_002287
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UniProt
- Q14739
Target
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