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Lymphoid Enhancer-Binding Factor 1 (LEF1) Peptide

LEF1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN979264
  • Target See all LEF1 products
    LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-LEF1 antibody (Catalog #: ARP32404_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
    Synonyms
    LEF1 Peptide, 3000002B05 Peptide, AI451430 Peptide, Lef-1 Peptide, LEF-1 Peptide, TCF10 Peptide, TCF1ALPHA Peptide, TCF7L3 Peptide, lymphoid enhancer binding factor 1 Peptide, lymphoid enhancer-binding factor 1 Peptide, lymphoid enhancer factor XLEF-1B Peptide, LEF1 Peptide, lef1 Peptide, Lef1 Peptide
    Background
    Lymphoid enhancer-binding factor-1 (LEF1) is a 48-kD nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha (TCRA) enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1 (HMG1).

    Alias Symbols: DKFZp586H0919, FLJ46390, TCF1ALPHA, LEF-1, TCF10, TCF7L3

    Protein Interaction Partner: CTNNB1,SMAD3,TLE1,ALX4,CDX1,CTNNB1,EP300,KPNA1,KPNA2,MITF,NLK,NOTCH1,PIAS4,PITX2,RUNX2,SMAD1,SMAD2,SMAD3,SMAD4,SUMO2,THOC4,TLE1,UBTF,ALX4,CTNNB1,EP300,Kpna1,Kpna2,MITF,NLK,NOTCH1,PIAS4,RUNX1,RUNX2,RUVBL1,SMAD2,SMAD3,SMAD4,SMAD7,THOC4,TLE1,UBTF

    Protein Size: 399
    Molecular Weight
    44 kDa
    Gene ID
    51176
    NCBI Accession
    NM_016269, NP_057353
    UniProt
    Q9UJU2
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