Lymphoid Enhancer-Binding Factor 1 (LEF1) Peptide
Quick Overview for Lymphoid Enhancer-Binding Factor 1 (LEF1) Peptide (ABIN979264)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-LEF1 antibody (Catalog #: ARP32404_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
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Background
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Lymphoid enhancer-binding factor-1 (LEF1) is a 48-kD nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha (TCRA) enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1 (HMG1).
Alias Symbols: DKFZp586H0919, FLJ46390, TCF1ALPHA, LEF-1, TCF10, TCF7L3
Protein Interaction Partner: CTNNB1,SMAD3,TLE1,ALX4,CDX1,CTNNB1,EP300,KPNA1,KPNA2,MITF,NLK,NOTCH1,PIAS4,PITX2,RUNX2,SMAD1,SMAD2,SMAD3,SMAD4,SUMO2,THOC4,TLE1,UBTF,ALX4,CTNNB1,EP300,Kpna1,Kpna2,MITF,NLK,NOTCH1,PIAS4,RUNX1,RUNX2,RUVBL1,SMAD2,SMAD3,SMAD4,SMAD7,THOC4,TLE1,UBTF
Protein Size: 399 -
Molecular Weight
- 44 kDa
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Gene ID
- 51176
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NCBI Accession
- NM_016269, NP_057353
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UniProt
- Q9UJU2
Target
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