Eukaryotic Translation Initiation Factor 2D (EIF2D) (Middle Region) Peptide
Quick Overview for Eukaryotic Translation Initiation Factor 2D (EIF2D) (Middle Region) Peptide (ABIN979291)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-LGTN antibody (Catalog #: ARP40690_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EIF2D (Eukaryotic Translation Initiation Factor 2D (EIF2D))
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Background
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LGTN is a protein receptor that localizes phosphoglycoproteins within endosomes and at the cell periphery. This trafficking receptor for phosphoglycoproteins may play a role in neuroplasticity by modulating cell-cell interactions, intracellular adhesion, and protein binding at membrane surfaces. In hippocampal neurons, long-lasting down-regulation of ligatin mRNA levels occurs via post-transcriptional RNA processing following glutamate receptor activation. This protein contains single PUA and SUI1 domains and these domains may function in RNA binding and translation initiation, respectively.This gene encodes a protein receptor that localizes phosphoglycoproteins within endosomes and at the cell periphery. This trafficking receptor for phosphoglycoproteins may play a role in neuroplasticity by modulating cell-cell interactions, intracellular adhesion, and protein binding at membrane surfaces. In hippocampal neurons, long-lasting down-regulation of ligatin mRNA levels occurs via post-transcriptional RNA processing following glutamate receptor activation. This protein contains single PUA and SUI1 domains and these domains may function in RNA binding and translation initiation, respectively.
Alias Symbols: HCA56, LGTN
Protein Interaction Partner: ACHE,HEXB,RAD51
Protein Size: 584 -
Molecular Weight
- 65 kDa
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Gene ID
- 1939
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NCBI Accession
- NM_006893, NP_008824
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UniProt
- P41214
Target
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