Ligase I, DNA, ATP-Dependent (LIG1) (Middle Region) Peptide
LIG1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979314
Quick Overview for Ligase I, DNA, ATP-Dependent (LIG1) (Middle Region) Peptide (ABIN979314)
Target
LIG1
(Ligase I, DNA, ATP-Dependent (LIG1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- PSVTSFILDT EAVAWDREKK QIQPFQVLTT RKRKEVDASE IQVQVCLYAF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-LIG1 Antibody(ARP54308_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))
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Background
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LIG1is DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.
Alias Symbols: MGC117397, MGC130025
Protein Interaction Partner: PCNA,CSNK2A1,INPP1,MRE11A,PCNA,TUBB3,MRE11A,PCNA,UBC
Protein Size: 919 -
Molecular Weight
- 102 kDa
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Gene ID
- 3978
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NCBI Accession
- NM_000234, NP_000225
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UniProt
- P18858
Target
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