Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) (N-Term) Peptide
LPCAT2
Reactivity: Mouse
Host: Synthetic
BP, WB
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- Target See all LPCAT2 products
- LPCAT2 (Lysophosphatidylcholine Acyltransferase 2 (LPCAT2))
- Protein Region
- N-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NENAQTPLVG RLLRALQPVL VSRVDPDSRK NTINEIKKRA TSGGEWPQIL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Lpcat2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- LPCAT2 (Lysophosphatidylcholine Acyltransferase 2 (LPCAT2))
- Background
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Lpcat2 possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. It is involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). It also converts lyso-PAF to 1-alkyl-phosphatidylcholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases.
Alias Symbols: A330042H22, Aytl1, LPCAT2, lpafat1, Aytl1a
Protein Size: 544 - Molecular Weight
- 60 kDa
- Gene ID
- 270084
- NCBI Accession
- NM_173014, NP_766602
- UniProt
- Q8BYI6
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