Lysocardiolipin Acyltransferase 1 (LCLAT1) (Middle Region) Peptide
LCLAT1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979661
Quick Overview for Lysocardiolipin Acyltransferase 1 (LCLAT1) (Middle Region) Peptide (ABIN979661)
Target
LCLAT1
(Lysocardiolipin Acyltransferase 1 (LCLAT1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-LYCAT antibody (Catalog #: ARP44426_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))
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Background
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LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.
Alias Symbols: ALCAT1, FLJ37965, UNQ1849, LYCAT, AGPAT8, 1AGPAT8, HSRG1849
Protein Size: 376 -
Molecular Weight
- 44 kDa
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Gene ID
- 253558
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NCBI Accession
- NM_001002257, NP_001002257
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UniProt
- Q6UWP7
Target
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