Melanoma Antigen Family D, 1 (MAGED1) (C-Term) Peptide
Quick Overview for Melanoma Antigen Family D, 1 (MAGED1) (C-Term) Peptide (ABIN979740)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- ACFVLEKKFG IQLKEIDKEE HLYILISTPE SLAGILGTTK DTPKLGLLLV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAGED1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
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Background
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This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: DLXIN-1, NRAGE
Protein Interaction Partner: TRAF4,BRP44L,DLX4,DLX5,EIF3J,GPR135,MAGED1,MSX2,NGFR,PJA1,PJA2,PLK1,RBFOX1,RFX1,ROR2,SIRT7,TRAF4,TUBA4A,XIAP,AATF,AKAP8L,ATXN10,BAG6,BRP44L,CALML5,CCDC59,COPG,COPG2,EBNA-LP,EIF3E,EIF3J,FANCI,GCN1L1,GPR135,HEATR1,HEATR2,HSPB1,IARS,IRAK1,KIAA1967,LRPPRC,MTHFD1L,NEDD8,NGFR,NOC2L,NUP160,NUP205,PJA1,PJA2,PLK1,RFX1,RNF185,ROR2,SIRT7,SLC25A1,SMC3,SPTLC1,TELO2,TIMM50,TOLLIP,Tuba1a,UBC,UBR5,UNC5A,XIAP
Protein Size: 778 -
Molecular Weight
- 86 kDa
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Gene ID
- 9500
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NCBI Accession
- NM_006986, NP_008917
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UniProt
- Q9Y5V3
Target
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