Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (N-Term) Peptide
Quick Overview for Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (N-Term) Peptide (ABIN979770)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- SNSLKKSSAE LRKILANGQM NEQDIRYRDT LGHGNGGTVY KAHHVPSGKI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Map2k5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
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Background
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Map2k5 acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.
Alias Symbols: AI324775, AI428457, MEK5, Mapkk5, Prkmk5
Protein Interaction Partner: Map3k2,Map3k3,Pard6a
Protein Size: 448 -
Molecular Weight
- 50 kDa
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Gene ID
- 23938
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NCBI Accession
- NM_011840, NP_035970
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UniProt
- Q9WVS7
Target
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