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Microtubule-Associated Protein 4 (MAP4) (N-Term) Peptide

MAP4 Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN979782

Quick Overview for Microtubule-Associated Protein 4 (MAP4) (N-Term) Peptide (ABIN979782)

Target

MAP4 (Microtubule-Associated Protein 4 (MAP4))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

N-Term

Sequence

LKETERASPI KMDLAPSKDM GPPKENKKET ERASPIKMDL APSKDMGPPK

Characteristics

This is a synthetic peptide designed for use in combination with anti-MAP4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
Microtubule-Associated Protein 4 (MAP4) peptide
MAP4 Reactivity: Mammalian Host: Synthetic BP, WB, IHC

Microtubule-Associated Protein 4 (MAP4) (N-Term) peptide
MAP4 Reactivity: Human Host: Synthetic BP, WB

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

MAP4 (Microtubule-Associated Protein 4 (MAP4))

Background

MAP4 is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression.

Alias Symbols: DKFZp779A1753, MGC8617

Protein Interaction Partner: CCNB1,MARK4,TUBB,CCNB1,CDK1,ENO2,MARK1,MARK4,NR1I3,RXRB,RXRG,TUBB,CDK1,ENO2,FYCO1,MARK4

Protein Size: 1152

Molecular Weight

121 kDa

Gene ID

4134

NCBI Accession

NM_002375, NP_002366

UniProt

P27816

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