Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) Peptide
MAP4K1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979783
Quick Overview for Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) Peptide (ABIN979783)
Target
MAP4K1
(Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAP4K1 antibody (Catalog #: ARP46044_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))
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Background
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MAP4K1 belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily. MAP4K1 may play a role in the response to environmental stress. It appears to act upstream of the JUN N-terminal pathway. MAP4K1 may play a role in hematopoietic lineage decisions and growth regulation.
Alias Symbols: HPK1
Protein Interaction Partner: CRK,CRKL,GRAP2,GRB2,ABL1,BLNK,CASP3,CRK,CRKL,DAPP1,DBNL,EGFR,GRAP2,GRB2,HCLS1,LAT,LCP2,LYN,MAP3K11,MAP3K7,MAP4K1,MAP4K1,NCK1,SHC1,SYK,BLNK,CRK,CRKL,DBNL,EGFR,GRAP2,GRB2,HCLS1,LAT,MAP3K11,MAP3K7,NCK1
Protein Size: 821 -
Molecular Weight
- 90 kDa
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Gene ID
- 11184
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NCBI Accession
- NM_001042600, NP_001036065
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UniProt
- A8MWC4
Target
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