Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) (N-Term) Peptide
MAP4K2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979784
Quick Overview for Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) (N-Term) Peptide (ABIN979784)
Target
MAP4K2
(Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAP4K2 antibody (Catalog #: ARP48631_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))
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Background
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MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
Alias Symbols: BL44, GCK, RAB8IP
Protein Interaction Partner: MAP3K1,TRAF2,MAP3K11,RAB8A,TRAF2,MAP2K4,MAP3K1,RAB8A,TRAF2
Protein Size: 820 -
Molecular Weight
- 91 kDa
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Gene ID
- 5871
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NCBI Accession
- NM_004579, NP_004570
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UniProt
- Q12851
Target
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