Mitogen-Activated Protein Kinase 13 (MAPK13) (Middle Region) Peptide
Quick Overview for Mitogen-Activated Protein Kinase 13 (MAPK13) (Middle Region) Peptide (ABIN979795)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- EMLTGKTLFK GKDYLDQLTQ ILKVTGVPGT EFVQKLNDKA AKSYIQSLPQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAPK13 Antibody(ARP56439_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAPK13 (Mitogen-Activated Protein Kinase 13 (MAPK13))
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Background
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.
Alias Symbols: MGC99536, PRKM13, SAPK4, p38delta
Protein Interaction Partner: ATF2,EEF2K,MAP2K6,MAP3K4,MAPKAPK3,MAPKAPK5,MBP,SMAD4,ATF2,FGF12,MAPK8IP2
Protein Size: 365 -
Molecular Weight
- 42 kDa
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Gene ID
- 5603
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NCBI Accession
- NM_002754, NP_002745
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UniProt
- Q9N272
Target
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