Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3) (N-Term) Peptide
MAPK8IP3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979804
Quick Overview for Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3) (N-Term) Peptide (ABIN979804)
Target
JIP3 (MAPK8IP3)
(Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- QYEREKALRR QAEEKFIEFE DALEQEKKEL QIQVEHYEFQ TRQLELKAKN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAPK8IP3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- JIP3 (MAPK8IP3) (Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3))
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Background
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The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport.
Alias Symbols: DKFZp762N1113, FLJ00027, JIP3, JSAP1, KIAA1066, SYD2, syd
Protein Size: 1330 -
Molecular Weight
- 147 kDa
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Gene ID
- 23162
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NCBI Accession
- NM_001040439, NP_001035529
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UniProt
- E9PFH7
Target
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