Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) (Middle Region) Peptide
MAPKAPK2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979806
Quick Overview for Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) (Middle Region) Peptide (ABIN979806)
Target
MAPKAP Kinase 2 (MAPKAPK2)
(Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- KLTDFGFAKE TTQNALQTPC YTPYYVAPEV LGPEKYDKSC DMWSLGVIMY
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAPKAPK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
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Background
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MAPKAPK2 is a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo.
Alias Symbols: 3PK, MAPKAP3, MK2, MK-2, MAPKAP-K2
Protein Interaction Partner: HNRNPA0,MDM2,ARPC5,MDM2,YWHAZ,YWHAZ,AKT1,ALOX5,ARPC5,BAG2,CREB1,EEF2K,ETV1,HNRNPA0,HSF1,HSPB1,LSP1,MAPK14,MAPKAPK2,PHC2,SHC1,SRF,TCF3,TH,TSC2,YWHAZ,ZFP36,AKT1,CDC25B,EGF,ETV1,HSPB1,HSPB1,MAPK1,MAPK14,PHC2,SHC1,Tsc2
Protein Size: 370 -
Molecular Weight
- 42 kDa
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Gene ID
- 9261
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NCBI Accession
- NM_004635, NP_004626
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UniProt
- Q16644
Target
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