Macrophage Receptor with Collagenous Structure (MARCO) (C-Term) Peptide
MARCO
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979830
Quick Overview for Macrophage Receptor with Collagenous Structure (MARCO) (C-Term) Peptide (ABIN979830)
Target
MARCO
(Macrophage Receptor with Collagenous Structure (MARCO))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- GPAGVKGEQG SPGLAGPKGA PGQAGQKGDQ GVKGSSGEQG VKGEKGERGE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MARCO Antibody(ARP41581_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
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Background
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The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
Alias Symbols: SCARA2
Protein Interaction Partner: SCGB3A1,SCGB3A2,SCGB3A1,SCGB3A2
Protein Size: 520 -
Molecular Weight
- 53 kDa
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Gene ID
- 8685
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NCBI Accession
- NM_006770, NP_006761
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UniProt
- Q9UEW3
Target
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